| SIM DIGITAL - POP INGLESES | — |  Brazil | — | — | — | OSM |
| SIN06 DC | — |  Singapore | — | — | — | OSM |
| SK Broadband IDC | SK브로드밴드 |  서울특별시 | — | — | — | OSM |
| SLRC KMC | Khyber Medical College |  Pakistan | — | — | — | OSM |
| SLT IDC - National Data Center - Pitipana | Sri Lanka Telecom PLC |  Pitipana | — | — | — | OSM |
| SM3 | Euro Information |  France | — | — | — | OSM |
| SM4 | Euro Information | France | — | — | — | OSM |
| SNCF | SNCF | France | — | — | — | OSM |
| SPACE-IX | RECONN. Operator Svyazi, LLC |  Moscow | — | — | — | PeeringDB |
| SPC3A | Google |  United States | — | — | — | OSM |
| SPC4A | Google | United States | — | — | — | OSM |
| SPHATIK NETWORK PRIVATE LIMITED | Sphatik Network Private Limited |  Jetpur | — | — | — | PeeringDB |
| SSE | SSE |  Havant | — | — | — | OSM |
| SSS & Company | — | Pakistan | — | — | — | OSM |
| ST1 | — |  Chile | — | — | — | OSM |
| STACK | Stack Infrastructure | Manassas | — | — | — | OSM |
| STACK Infrastructure OSL04 | STACK Infrastructure |  Norway | — | — | — | OSM |
| STACK MILL2 | STACK |  Italy | — | — | — | OSM |
| STACK NVA01A | STACK Infrastructure | Sterling | — | — | — | OSM |
| STACK NVA05A | — | Manassas | — | — | — | OSM |
| STACK NVA06 | STACK Infrastructure | United States | — | — | — | OSM |
| STACK NVA06 | STACK Infrastructure | United States | — | — | — | OSM |
| STACK New Albany | STACK Infrastructure | United States | — | — | — | OSM |
| STACK SVY02 | STACK Infrastructure | United States | — | — | — | OSM |
| STACK infrastructure ZUR01 | STACK Infrastructure |  Rafz | — | — | — | PeeringDB |
| STAR - TQR | Star - Internet e Telefonia | Taquara | — | — | — | PeeringDB |
| STAYBOX SERVICOS DE HOSPEDAGEM NA INTERNET | StayBox | Frederico Westphalen | — | — | — | PeeringDB |
| STNet | STNet |  Japan | — | — | — | OSM |
| STNet | 株式会社STNet(エスティネット) | Japan | — | — | — | OSM |
| STT Cavite 2 | STTGDC |  General Trias | — | — | — | PeeringDB |
| STT Davao | STTGDC | Davao | — | — | — | PeeringDB |
| STT Fairview Data Centre | ST Telemedia Global Data Centres | Philippines | — | — | — | OSM |
| STT Johor 1 | STTGDC |  Gelang Patah | — | — | — | PeeringDB |
| STT Kuala Lumpur 1 | STTGDC | Cyberjaya | — | — | — | PeeringDB |
| STT Mandaluyong | STTGDC | Mandaluyong | — | — | — | PeeringDB |
| STT Seoul 1 | STTGDC | Seoul | — | — | — | PeeringDB |
| STT Singapore 2 | STTGDC | Singapore | — | — | — | PeeringDB |
| STT Singapore 3 | STTGDC | Singapore | — | — | — | PeeringDB |
| STT Tokyo 1 | STTGDC | Inzai | — | — | — | PeeringDB |
| STT Tokyo 2 | STTGDC | Inzai | — | — | — | PeeringDB |
| STTelemedia Global Data Centeres | — | India | — | — | — | OSM |
| SU Green Data Center | Syracuse University | Onondaga | — | — | — | OSM |
| SULNET | Sulnet | Santa Rosa | — | — | — | PeeringDB |
| SWAN Datacentrum | SWAN |  Slovakia | — | — | — | OSM |
| SYMPHONY THAI - AIMS BANGKOK | Symphony Communication |  Bangkok | — | — | — | PeeringDB |
| SYMPHONY THAI - STT BANGKOK | Symphony Communication | Bangkok | — | 1 | — | PeeringDB |
| Sabay Digital - Tonle Basak (KPH) | Sabay TeKh |  Phnom Penh | — | 1 | — | PeeringDB |
| Sabey Data Centers | Sabey Data Centers |  Germany | — | — | — | OSM |
| SafeDX s.r.o. | SafeDX |  Czechia | — | — | — | OSM |
| Sajjad Serves | — | Pakistan | — | — | — | OSM |
| Sala E | — |  Colombia | — | — | — | OSM |
| Salle Serveurs CCCM | — | France | — | — | — | OSM |
| Salle Technique France Télévisions | France Télévisions | France | — | — | — | OSM |
| Salle Technique France Télévisions | France Télévisions | France | — | — | — | OSM |
| Salle Technique France Télévisions | France Télévisions | France | — | — | — | OSM |
| Salle Technique Groupe Canal | Groupe Canal | France | — | — | — | OSM |
| Salle Technique TV5MONDE | TV5MONDE | France | — | — | — | OSM |
| Salle technique Euronews | Euronews | France | — | — | — | OSM |
| Salle technique Eurosport | Eurosport | France | — | — | — | OSM |
| Salle technique Groupe CANAL | Groupe CANAL | France | — | — | — | OSM |
| Salle technique Groupe M6 | Groupe M6 | France | — | — | — | OSM |
| Salle technique Groupe M6 | Groupe M6 | France | — | — | — | OSM |
| Salle technique TDF | TDF | France | — | — | — | OSM |
| Salle technique TF1 | TF1 | France | — | — | — | OSM |
| Samaee Server | بهنام سمائی Behnam Samaee |  Iran | — | — | — | OSM |
| Sampark | SamparK | Mumbai | — | — | — | PeeringDB |
| Samz Broadband Networx | Samz Broadband Networx ( SMC-PRIVATE ) | Lahore | — | — | — | PeeringDB |
| San Martin | S3 Simple Smart Speedy | Bogota | — | — | — | PeeringDB |
| Santander | Santander | United Kingdom | — | — | — | OSM |
| Santander | Santander | United Kingdom | — | — | — | OSM |
| Santander | Santander | United Kingdom | — | — | — | OSM |
| Sartera | Sartel | France | — | — | — | OSM |
| SaskTel | — |  Canada | — | — | — | OSM |
| SaskTel | — | Canada | — | — | — | OSM |
| Satelitsko i multimedijsko središte Deanovec | Odašiljači i veze d.o.o. |  Croatia | — | — | — | OSM |
| Scala Data Centers SGIGSM01 | Scala Data Centers | Sao Joao de Meriti | — | 1 | — | PeeringDB |
| Scala Data Centers SGRUTB03 | Scala Data Centers | Barueri | — | — | 1 | PeeringDB |
| Scala Data Centers SGRUTB04 | Scala Data Centers | Barueri | — | — | — | PeeringDB |
| Scala Data Centers SGRUTB05 | Scala Data Centers | Barueri | — | — | — | PeeringDB |
| Scala Data Centers SGRUTB08 | Scala Data Centers | Barueri | — | — | — | PeeringDB |
| Scala Data Centers SGRUTB12 | Scala Data Centers | Tamboré | — | — | — | PeeringDB |
| Scala Data Centers SSCLCR01 | Scala Data Centers | Placilla | — | 1 | — | PeeringDB |
| Scala Data Centers SVCPCP01 | Scala Data Centers | Campinas | — | — | 1 | PeeringDB |
| ScaleMatrix Jacksonville Data Center US-South 02 | ScaleMatrix Holdings | Jacksonville | — | — | — | PeeringDB |
| ScaleMatrix Seattle Data Center US-West 02 | ScaleMatrix Holdings | Puyallup | — | — | — | PeeringDB |
| Scientific Computing Center | — | Germany | — | — | — | OSM |
| Scitis-Zen DataCenter Hitachi | — | Ardon | — | — | — | OSM |
| Searcy Information Technologies | City of Searcy | Searcy | — | — | — | OSM |
| SecrelNet Informática Fortaleza | SECRELNET INFORMATICA LTDA | Fortaleza | — | — | — | PeeringDB |
| Secure Data Center | — | United States | — | — | — | OSM |
| Secure Data Center Bekkan | SECOM Trust Systems | Mitaka | — | — | — | PeeringDB |
| Secure Data Center Osaka | SECOM Trust Systems | Osaka | — | — | — | PeeringDB |
| Secure Data Center Shinkan | SECOM Trust Systems | Mitaka | — | — | — | PeeringDB |
| Secure Data Center TC4 | SECOM Trust Systems | Mitaka | — | — | — | PeeringDB |
| SecureData 365 | SecureData 365 | Canton | — | — | 1 | PeeringDB |
| SecureIT DCB1.1 | SecureIT S.A. |  Bettembourg | — | — | — | PeeringDB |
| SecureIT DCB1.2 | SecureIT S.A. | Bettembourg | — | — | — | PeeringDB |
| Segra Data Center | — | Raleigh | — | — | — | OSM |
| Seixal Colocation Site | TATA Communications |  Portugal | — | — | — | OSM |
| Senawave | Senawave | Salt Lake City | — | — | — | PeeringDB |